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Insula

April 28, 2010

/www.ncbi.nlm.nih.gov/pubmed/20368513

Neural processing of reward and loss in girls at risk for major depression

RESULTS: While anticipating gains, high-risk participants showed less activation than did their low-risk counterparts in the putamen and left insula but showed greater activation in the right insula. When receiving punishment, high-risk participants showed greater activation in the dorsal anterior cingulate gyrus than did low-risk participants, who showed greater activation in the caudate and putamen.

Putamen = reward assessment .Less activated if your’e downbeat.

ACC = conflict resolution in loss situations = higher activation in downbeats because they will exaggerate losses ?

Role of Left Insula ??

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